(x-active)
57 -- Bobby Thigpen, Chicago White Sox, 1990
55 -- John Smoltz, Atlanta, 2002
55 -- Eric Gagne, L.A. Dodgers, 2003
54 -- x-Francisco Rodriguez, L.A. Angels, 2008
53 -- Mariano Rivera, New York Yankees, 2004
53 -- Trevor Hoffman, San Diego, 1998
53 -- Randy Myers, Chicago Cubs, 1993
52 -- Eric Gagne, L.A. Dodgers, 2002
51 -- Dennis Eckersley, Oakland, 1992
51 -- Rod Beck, Chicago Cubs, 1998
50 -- Mariano Rivera, New York Yankees, 2001
49 -- Francisco Cordero, Texas, 2004
48 -- Dennis Eckersley, Oakland, 1990
48 -- Rod Beck, San Francisco, 1993
48 -- Jeff Shaw, Cincinnati-L.A. Dodgers, 1998
47 -- Chad Cordero, Washington, 2005
47 -- Jose Valverde, Arizona, 2007
47 -- Armando Benitez, Florida, 2004
47 -- Francisco Rodriguez, L.A. Angels, 2006
47 -- Jason Isringhausen, St. Louis, 2004
47 -- Lee Smith, St. Louis, 1991