Two of the league's top rookie quarterbacks will square off when the Dallas Cowboys host the Philadelphia Eagles on Sunday night.
Dak Prescott and the Cowboys are coming off a bye and looking to stay on track against Carson Wentz and the Eagles.
Here's a closer look at the rest of Week 8:
Jacksonville Jaguars at Tennessee Titans, 8:25 p.m. ET Thursday
Jacksonville Jaguars
The AFC South is again shaping up to be the worst division in the NFL, which means as poorly as the Jaguars have played, they're still nowhere close to being out of the race. That's what makes Thursday's game at Tennessee so important. Read more
Tennessee Titans
Two teams yet to find solid footing in the AFC South square off at Nissan Stadium with last place on the line. The 3-4 Titans host the 2-4 Jaguars in a Color Rush game where it'll look like the sky is playing against mustard. Read more
Washington Redskins at Cincinnati Bengals, 9:30 a.m. Sunday
Washington Redskins
Even though the Bengals are 3-4, they still have the core of the franchise that helped them win double-digit games in each of the previous four seasons. The Redskins last did that from 1983 to 1987 when they were playing in -- and winning -- Super Bowls. Read more
Cincinnati Bengals
The Washington Redskins' secondary is probably bracing for Bengals wide receiver A.J. Green this week. They just might have to figure out how to stop him without their best cornerback, Josh Norman. Read more
Kansas City Chiefs at Indianapolis Colts, 1 p.m. ET Sunday
Kansas City Chiefs
The 4-2 Chiefs will face their third straight opponent ranked in the top 10 in scoring when they play the 3-4 Colts in Indianapolis. The Colts are averaging almost 28 points per game, fourth-best in the league. Read more
Indianapolis Colts
Sunday marks the first meeting between the Colts and Chiefs since Andrew Luck led Indianapolis from a 28-point third-quarter deficit in their 45-44 AFC wild-card playoff matchup in January 2014. Read more
Oakland Raiders at Tampa Bay Buccaneers, 1 p.m. ET Sunday
Oakland Raiders
The Raiders are in a kind of training camp mode as they spend the week in Florida between games at the Jaguars, a 33-16 victory, and the Buccaneers. Read more
Tampa Bay Buccaneers
The Tampa Bay Buccaneers return home for the first time in nearly a month Sunday to take on the Oakland Raiders, who are 4-0 on the road this season, 5-2 overall and first in the AFC West. The Bucs are 3-3 and have won two in a row but have yet to win at home. Read more
Seattle Seahawks at New Orleans Saints, 1 p.m. ET Sunday
Seattle Seahawks
The Seahawks' defense enters the game allowing 14 points per game, tied for best in the NFL. The Saints, meanwhile, are averaging 29.3 points per game on offense, second-best. Read more
New Orleans Saints
Jimmy Graham's return to the Mercedes-Benz Superdome will obviously be the marquee event. But the matchup between the New Orleans Saints' offense and the Seattle Seahawks' defense could be even more compelling. Read more
Detroit Lions at Houston Texans, 1 p.m. ET Sunday
Detroit Lions
Facing a beat-up Houston Texans team on a short week, it could be a chance for the Lions to pick up a critical road win and their fourth straight victory. Read more
Houston Texans
Matthew Stafford has been playing like a legitimate MVP candidate, so he will be a tough test for a banged-up Texans secondary, especially when he is throwing to receiver Marvin Jones. Read more
New York Jets at Cleveland Browns, 1 p.m. ET Sunday
New York Jets
You think the Jets are dealing with quarterback instability? Not compared to the Browns, who have started 26 different quarterbacks since 1999. It'll be 27 if Kevin Hogan starts Sunday against the Jets. Read more
Cleveland Browns
The Jets provide the Browns with an opportunity for their first win. ESPN Analytics gives the Browns a 39.6 percent chance, which is higher than the team's chance to win any other game the rest of the season. Read more
New England Patriots at Buffalo Bills, 1 p.m. ET Sunday
New England Patriots
Who the Patriots decide to focus on starts with running back LeSean McCoy, who was a handful when the two teams met Oct. 2. Read more
Buffalo Bills
Patriots quarterback Tom Brady will be a new challenge for a defense that has shown promise at times but has also been porous on other occasions. Read more
Arizona Cardinals at Carolina Panthers, 1 p.m. ET Sunday
Arizona Cardinals
The Panthers ended Arizona’s season in the wild-card round in 2014. Last year, they sent the Cardinals home with a beatdown in the NFC Championship Game. Revenge? Read more
Carolina Panthers
If Carolina can shore up issues in the secondary to get the defense back to the top-10 level it has been the past three years, it has the talent offensively to score a lot of points and get on a roll. Read more
San Diego Chargers at Denver Broncos, 4:05 p.m. ET Sunday
San Diego Chargers
The Chargers still have not won on the road in the AFC West in over two years, last defeating the Oakland Raiders in the Oakland-Alameda County Coliseum, 31-28 on Oct. 12, 2014. The Chargers also have not swept the Broncos in a season series since 2010. Read more
Denver Broncos
A lot can happen in 17 days. And for the second time in a three-game span, the Broncos will face the Chargers. The Chargers will likely see a different Broncos team than the one that slogged around in Qualcomm Stadium earlier this month. Read more
Green Bay Packers at Atlanta Falcons, 4:25 p.m. ET Sunday
Green Bay Packers
Packers coach Mike McCarthy said one stat says everything you need to know about the Falcons. "They're No. 1 in the league in scoring," the Green Bay Packers coach said. "I think that tells you the story." Read more
Atlanta Falcons
The game is sure to be built up as a matchup of top quarterbacks, as Matt Ryan of the Falcons and Aaron Rodgers of the Packers do battle at the Georgia Dome. The two have met five times before, with Rodgers holding a 3-2 advantage. Read more
Philadelphia Eagles at Dallas Cowboys, 8:30 p.m. ET Sunday
Philadelphia Eagles
The Cowboys have one of the top offensive lines in football and an elite rookie back in Ezekiel Elliott. That has helped the cause of first-year quarterback Dak Prescott, who has completed 68.7 percent of his passes with seven touchdowns and one interception. Read more
Dallas Cowboys
Most of the headlines will center on rookie quarterbacks Dak Prescott and Carson Wentz. According to Elias, this is the first time since the 1970 merger that rookie quarterbacks will meet with a combined winning percentage of .750 or better with a minimum of three starts. Read more
Minnesota Vikings at Chicago Bears, 8:30 p.m. ET Monday
Minnesota Vikings
Jay Cutler, the Bears' sometimes-loved, often-loathed quarterback, has been cleared to return from a thumb injury, and he should start just his third game of the season against a team he has beaten eight times in 13 career starts. Read more
Chicago Bears
History is on Chicago's side. The Bears had a five-game winning streak at home against Minnesota snapped last year, when the Vikings swept the season series for the first time since 2007. Read more