OMAHA, Neb. -- Quick thoughts from Norfolk State's 86-84 upset win over second-seeded Missouri.

Overview: As if George Mason and VCU weren't enough, another unlikely March hero has emerged from the state of Virginia.

Norfolk State -- a school of about 6,000 that had never appeared in the NCAA tournament -- shocked Final Four favorite Missouri before a sellout crowd of 16,843 fans Friday at the CenturyLink Center in Omaha.

The victory marked the first time since 2001, when Hampton defeated Iowa State, that a No. 15 seed has defeated a No. 2 seed. Kyle O'Quinn scored 26 points for Norfolk State, which advanced to play Florida on Sunday for a trip to the Sweet 16. Missouri ends its season with a record of 30-5.

Trailing by two points with 2.8 seconds remaining, Missouri had a chance to win. Tigers guard Phil Pressey took an inbounds pass near midcourt, took a few dribbles and got off a decent look from 3-point range. The shot clanged off the side of the rim as the horn sounded, setting off a wild celebration by Norfolk State.

Norfolk State took the lead for good with 34.9 seconds remaining when O'Quinn snared the offensive rebound of a teammate's air ball and put it back in for an easy two points while being fouled. O'Quinn converted the ensuing free throw to make it 84-81.

Missouri's Marcus Denmon missed an ill-advised, deep 3-pointer early in the shot clock on the Tigers' next possession. O'Quinn got the rebound and was immediately fouled. He made one of two free throws to put Norfolk State ahead 85-81 with 16 ticks left.

Pressey, who was brilliant down the stretch for Missouri, made a 3-pointer with 10 seconds left to pull Missouri within a point, 85-84. Rodney McCauley was fouled by Missouri, and he made the first of two free throws to extend the Spartans' lead to 86-84. O'Quinn snared the rebound on McCauley's miss, and a jump ball was called when O'Quinn became tied up with a Missouri player. O'Quinn missed both foul shots, and Missouri called a timeout to set up the final shot by Pressey, which was off the mark.

Along with his 26 points, O'Quinn added 14 rebounds for Norfolk State. Chris McEachin had 20 points. Michael Dixon (22 points), Pressesy and Denmon (20 points each) all had good games for Missouri.

Player of the game: O'Quinn is an absolute beast. He clearly outplayed Missouri forward Ricardo Ratliffe and was a flat-out warrior throughout the entire game. The 6-foot-10, 240-pounder has an exceptional shooting touch for his size and can handle the ball.

Key stat: Both teams were on fire Friday. Norfolk State shot 54 percent from the field, Missouri 52 percent.

Miscellaneous: Even though Omaha is somewhat close to Columbia, Missouri must have felt like the road team Friday. More than half the CenturyLink Center was filled with Kansas fans cheering for Norfolk State. The Jayhawks, Missouri's Big 12 rival, take on Detroit here later tonight.

Up next: Norfolk State will play Florida on Sunday for a chance to go to the Sweet 16. For Missouri, it's over. The next time we see the Tigers, they'll be official members of the SEC.